Cancer and age related colonic crypt deficiencies in cytochromecoxidase I
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چکیده
منابع مشابه
Age-related alterations in blood and colonic dendritic cell properties
BACKGROUND Dendritic cells (DC) determine initiation, type and location of immune responses and, in adults, show decreased Toll-like receptors and some increased cytokine levels on ageing. Few studies in children have characterised DC or explored DC-related mechanisms producing age-related immune changes. RESULTS The pDC marker BDCA2 (but not CD123) was absent in pre-pubertal children and num...
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Based on investigation of the earliest colonic tissue alteration in familial adenomatous polyposis (FAP) patients, we present the hypothesis that initiation of colorectal cancer by adenomatous polyposis coli (APC) mutation is mediated by dysregulation of two cellular mechanisms. One involves differentiation, which normally decreases the proportion (proliferative fraction) of colonic crypt cells...
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ژورنال
عنوان ژورنال: World Journal of Gastrointestinal Oncology
سال: 2010
ISSN: 1948-5204
DOI: 10.4251/wjgo.v2.i12.429